Patent · US Active

Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor I

US10189821B2 · kind B2 · utility

4Cited by
4References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 24, 2016
Grant dateJan 29, 2019
Priority date
Expiry dateOct 24, 2036

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D491/056
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to compounds of formula I as defined herein. The compounds of the present invention are inhibitors of heat shock factor 1 (HSF1). In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.