Neprilysin inhibitors
US10189823B2 · kind B2 · utility
9Cited by
33References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 14, 2017 |
| Grant date | Jan 29, 2019 |
| Priority date | — |
| Expiry date | Dec 14, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D263/38
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In one aspect, the invention relates to compounds having the formula: where X, Ra, Rb, R2, and R7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds are prodrugs of compounds having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.