Wnt pathway modulators
US10189842B2 · kind B2 · utility
2Cited by
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10Claims
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Key dates
| Filing date | Dec 17, 2014 |
| Grant date | Jan 29, 2019 |
| Priority date | — |
| Expiry date | Dec 17, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to dihydropyrazolo[1,5-a]pyrimidine compounds of formula I, defined herein, as WNT pathways modulators, processes for making them, and pharmaceutical compositions comprising them. Methods of treatment of conditions mediated by WNT pathway signalling including cancer, fibrosis, stem cell and diabetic retinopathy, rheumatoid arthritis, psoriasis and myocardial infarction, comprising the compounds of formula I are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.