Ebolavirus pre-hairpin intermediate mimics and methods of use
US10189878B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Sep 24, 2015 |
| Grant date | Jan 29, 2019 |
| Priority date | — |
| Expiry date | Sep 24, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Ebolavirus is a highly lethal filovirus that causes hemorrhagic fever in humans and non-human primates. With no approved treatments or preventatives, the development of an anti-ebolavirus therapy to protect against natural infections and potential weaponization is an urgent unmet global health need. The design, biophysical characterization, and validation of peptide mimics of the ebolavirus N-trimer (“N-trimer mimics”) are described herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.