Method for synthesizing selectively labeled RNA

US10190143B2 · kind B2 · utility

Assignees

• The Board of Regents of the University of Texas System · US
• THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, OFFICE OF TECHNOLOGY TRANSFER—NATIONAL INSTITUTES OF HEALTH · US

Inventors

• Yun-Xing Wang · Columbia, US
• Yu Liu · Malvern, US
• Rui Sousa · San Antonio, US

Key dates

• Filing date: Jul 8, 2014
• Grant date: Jan 29, 2019
• Expiry date: Jul 15, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q1/6844
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to a method for synthesizing a selectively labeled RNA, and an apparatus for performing the method. Specific segments or discrete residues within the RNA may be selectively labeled, and different segments may include different labels.