Methods for identifying dendritic cell subsets, for determining if a patient is developing a regulatory or an effector immune response, and for determining response to immunotherapy

US10190166B2 · kind B2 · utility

Assignee

• STALLERGENES · FR

Inventors

• Philippe Moingeon · Verrières-le-Buisson, FR
• Aline Zimmer · Groß-Gerau, DE
• Julien Bouley · Montrouge, FR
• Laurent Mascarell · Paris, FR
• Emmanuel Nony · Antony, FR

Key dates

• Filing date: Sep 5, 2012
• Grant date: Jan 29, 2019
• Expiry date: May 21, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/158
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention concerns methods for determining if a dendritic cell belongs to a tolerogenic dendritic cell subset or to an effector dendritic cell subset, and methods for determining if a patient undergoing immunotherapy, and/or who has been administered with a vaccine, is developing an immune response oriented either towards a regulatory T cell response or towards an effector T cell response, and methods of determining response to immunotherapy.