Thyroglobulin quantitation by mass spectroscopy
US10191064B2 · kind B2 · utility
18Cited by
13References
9Claims
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Key dates
| Filing date | Feb 27, 2018 |
| Grant date | Jan 29, 2019 |
| Priority date | — |
| Expiry date | Feb 27, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/7028
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided are methods for determining the amount of thyroglobulin in a sample using various purification steps followed by mass spectrometry. The methods generally involve purifying thyroglobulin in a test sample, digesting thyroglobulin to form peptide T129, purifying peptide T129, ionizing peptide T129, detecting the amount of peptide T129 ion generated, and relating the amount of peptide T129 ion to the amount of thyroglobulin originally present in the sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.