Methods for therapeutic renal denervation

US10194983B2 · kind B2 · utility

Assignee

• MEDTRONIC ARDIAN LUXEMBOURG S.A.R.L. · LU

Inventors

• Neil Barman · Menlo Park, US
• Howard R. Levin · Teaneck, US
• Paul A. Sobotka · Windom, US
• Mark Gelfand · New York, US

Key dates

• Filing date: Dec 11, 2017
• Grant date: Feb 5, 2019
• Expiry date: Dec 11, 2037

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61N1/326
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Methods for therapeutic renal denervation are disclosed herein. One aspect of the present application, for example, is directed to methods that block, reduce and/or inhibit renal sympathetic nerve activity to achieve a reduction in central sympathetic tone. Renal sympathetic nerve activity may be altered or modulated along the afferent and/or efferent pathway. The achieved reduction in central sympathetic tone may carry several therapeutic benefits across many disease states.