Nanofibrous biologic heart valve leaflets and fibrosa layer of a leaflet
US10195022B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | Apr 12, 2016 |
| Grant date | Feb 5, 2019 |
| Priority date | — |
| Expiry date | May 30, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/20
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Systems and methods for producing biologic tissues are described. For example, this document provides electrospinning systems and culturing techniques to make biologic heart valve leaflets and fibrosa layers of native valve leaflet having nanofibrous substrate layer(s). In some implementations, a tri-layered leaflet with circumferentially, randomly, and radially oriented nanofibers that mimics morphologies of native leaflets.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.