Continuous process for preparing microspheres and microspheres prepared thereby
US10195149B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 15, 2014 |
| Grant date | Feb 5, 2019 |
| Priority date | — |
| Expiry date | May 15, 2034 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01F2101/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a continuous process for preparing microspheres and microspheres prepared thereby, and in particular, a process for preparing microspheres comprising steps of injecting a first emulsion and a second emulsion at the same time to form microspheres instantaneously, applying high pressure to the microspheres formed, and injecting the microspheres into an agitator, wherein the steps can be carried out continuously, and microspheres prepared thereby.When microspheres are prepared using the method of the present invention, scale variables, which have been the biggest disadvantage in existing preparation methods of microspheres, can be significantly reduced, drug encapsulation efficiency can be improved, and small and uniform particles can be obtained.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.