Fabrication process of phase-transition microneedle patch
US10195410B2 · kind B2 · utility
Inventor
Key dates
| Filing date | Jul 22, 2014 |
| Grant date | Feb 5, 2019 |
| Priority date | — |
| Expiry date | Apr 16, 2035 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB29L2031/753
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The application discloses a method to fabricate microneedle patches, comprising a) casting (painting and pasting) an aqueous polymer solution on a mold of array of micro-holes which is made of porous materials; b) sucking the polymer solution into the micro-holes by applying vacuum at the back of the mold; d) freezing and thawing the casted polymer solution to induce gelation; and e) drying the gelled polymer solution. Specifically, the present invention describes a process and composition of polymeric microneedlepatch which overcomes the limitations of existing microneedles systems and may be used for transdermal delivery system for therapeutics and other applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.