Glaucocalyxin a derivative and preparation method and application thereof

US10196344B2 · kind B2 · utility

Assignee

• SUZHOU PHARMAVAN CANCER RESEARCH CENTER CO., LTD. · CN

Inventors

• Haimei Feng · 安丰镇, CN
• Rensen Zhou · Suzhou, CN
• Xiang Chen · 安丰镇, CN
• Yunhui Yu · Suzhou, CN
• Qian Liu · Suzhou, CN
• Yong Li · Corvallis, US
• Shiping Deng · Hangzhou City, CN
• Chuangliang Jiang · 安丰镇, CN

Key dates

• Filing date: Dec 17, 2015
• Grant date: Feb 5, 2019
• Expiry date: Dec 17, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D473/18
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Provided is a glaucocalyxin A derivative, or salt thereof, as represented by the formula (I), a method for preparation of said glaucocalyxin A derivative, and a use for said glaucocalyxin A derivative in preparing pharmaceuticals for fighting autoimmune diseases and tumors, e.g. difficult-to-treat diseases such as systemic lupus erythematosus, psoriasis and triple-negative breast cancer