Synthetic biochemistry molecular purge valve module that maintain co-factor balance

US10196653B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• James U. Bowie · Culver City, US
• Paul H. Opgenorth · Sacramento, US
• Tyler P. Korman · Sierra Madre, US

Key dates

• Filing date: Apr 2, 2015
• Grant date: Feb 5, 2019
• Expiry date: Apr 2, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Y203/01012
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The disclosure provides a metabolic pathway for producing a metabolite, the metabolic pathway having a co-factor purge valve system for recycling a cofactor used in the metabolic pathway.