Microorganism for methionine production with improved methionine synthase activity and methionine efflux
US10196658B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 1, 2014 |
| Grant date | Feb 5, 2019 |
| Priority date | — |
| Expiry date | Sep 1, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y201/01013
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present application is related to a recombinant microorganism optimized for the fermentative production of methionine and/or its derivatives, wherein in said recombinant microorganism, the cobalamin-dependent methionine synthase activity and the methionine efflux are enhanced. The application is also related to a method for optimizing the fermentative production of methionine and/or its derivatives comprising the steps of: c. culturing a recombinant microorganism wherein in said microorganism, the cobalamin-dependent methionine synthase activity and the methionine efflux are enhanced, in an appropriate culture medium comprising a fermentable source of carbon and a source of sulphur, and d. recovering methionine and/or its derivatives from the culture medium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.