Colon cancer gene expression signatures and methods of use
US10196691B2 · kind B2 · utility
60Cited by
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14Claims
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Key dates
| Filing date | Jan 25, 2012 |
| Grant date | Feb 5, 2019 |
| Priority date | — |
| Expiry date | Jan 25, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A gene expression signature of colon cancer, microarrays including them and methods of using the colon gene expression signature are provided. The gene expression signature is especially useful for determining the prognosis of a patient diagnosed with colon cancer, such as stage II colon cancer. The gene signature described herein is also useful for determining effectiveness of surgical resection with or without adjuvant chemotherapy, and determining possibility of cancer recurrence in patients with colon cancer.
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