Polynucleotide primers for detecting PIK3CA mutations
US10196692B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Sep 18, 2015 |
| Grant date | Feb 5, 2019 |
| Priority date | — |
| Expiry date | Apr 11, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/16
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A polynucleotide comprising at least the final six nucleotides of one of the following primer sequences, or a sequence complementary thereto: SEQ. ID NOS. 3 to 16, 18, 20 to 33, 35 or 37 to 39. A method of detecting the presence or absence of a mutation in the PIK3CA gene, wherein the mutation is one of H1047R, H1047L, E542K and E545K, and preferably ARMS primers are combined with Scorpion primers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.