Process for reducing contaminating Michael acceptor levels in oxycodone and other compositions
US10201174B2 · kind B2 · utility
0Cited by
3References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 1, 2016 |
| Grant date | Feb 12, 2019 |
| Priority date | — |
| Expiry date | Aug 1, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/027
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to processes for removal of Michael acceptors from certain compositions wherein the composition is treated with a thiol-containing compound under conditions sufficient to remove Michael acceptors and the resulting thiol-Michael adducts. Certain embodiments of the present invention enable quantification and/or removal of Michael acceptors and/or Michael acceptor precursors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.