Inhibitors of leukotriene A4 hydrolase
US10202362B2 · kind B2 · utility
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13Claims
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Assignee
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Key dates
| Filing date | Dec 11, 2017 |
| Grant date | Feb 12, 2019 |
| Priority date | — |
| Expiry date | Dec 11, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This present disclosure is directed to compounds of formula (I):where R1a, R3, Y, and Z are described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, solvates, clathrates, polymorphs, ammonium ions, N-oxides or prodrugs thereof; which are leukotriene A4 hydrolase inhibitors and therefore useful in treating inflammatory disorders. Pharmaceutical compositions including the compounds described herein and methods of preparing the compounds described herein are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.