Patent · US Active

Benzimidazole derivatives as selective proteine kinase inhibitors

US10202370B2 · kind B2 · utility

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Key dates

Filing dateJun 20, 2014
Grant dateFeb 12, 2019
Priority date
Expiry dateJan 3, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed are compounds of formula I or pharmaceutically acceptable salts thereof: Wherein n, R1, R2, R3, R4, R5, A, Q and X are as defined in the description. These compounds selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant protein kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective native and/or mutant c-kit inhibitors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.