Patent · US Active

Detection of starch levels in biological matrices

US10202634B2 · kind B2 · utility

0Cited by

1References

19Claims

0Family size

Assignee

Fresenius Kabi Deutschland GmbH · DE

Inventors

Silke Baasner · Schöneck, DE
Frank Nocken · Frankfurt, DE
Klaus Biemel · Saarburg, DE

Key dates

Filing date	Dec 16, 2016
Grant date	Feb 12, 2019
Priority date	—
Expiry date	Jan 29, 2037

Classification

Technology area (CPC G)Physics
CPC primaryG01N2560/00
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Methods for detecting a starch in a sample are provided. The methods include the steps of initially incubating the sample in the presence of an amylase-containing medium and subsequently subjecting the sample to liquid chromatography mass spectrometry (LC-MS) to detect ions characteristic of the starch in the sample. The amylase-containing medium can include an amylase and blood plasma or the amylase-containing medium can include an amylase and a component selected from the group consisting of about 90-92% water or buffered water, about 8% protein, about 0.9% salt, and/or about 1.1% organic substances. The incubating step can be done in conditions that permit digestion of the starch by the amylase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.