Lyophilized formulation of TAT-NR2B9C with acetylation scavenger
US10206878B2 · kind B2 · utility
4Cited by
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16Claims
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Assignee
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Key dates
| Filing date | May 28, 2015 |
| Grant date | Feb 19, 2019 |
| Priority date | — |
| Expiry date | May 28, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides lyophilized formulations of active agents, particularly of TAT-NR2B9c including histidine, trehalose and lysine. TAT-NR2B9c has shown promise for treating stroke, aneurysm, subarachnoid hemorrhage and other neurological or neurotraumatic conditions. Such formulations are stable at ambient temperature thus facilitating maintenance of supplies of such a formulation in ambulances for administration at the scene of illness or accident or in transit to a hospital.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.