Patent · US Active

Small molecule inhibitors of EGFR and PI3K

US10206924B2 · kind B2 · utility

6Cited by
4References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 15, 2015
Grant dateFeb 19, 2019
Priority date
Expiry dateDec 15, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or a quinoline structure which function as dual inhibitors of EGFR proteins and PI3K proteins, and their use as therapeutics for the treatment of cancer and other diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.