Chloride salt of TAT-NR2B9c
US10206973B2 · kind B2 · utility
14Cited by
2References
34Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 28, 2015 |
| Grant date | Feb 19, 2019 |
| Priority date | — |
| Expiry date | May 28, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16322
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides lyophilized formulations of active agents, particularly of TAT-NR2B9c, as chloride salts. TAT-NR2B9c has shown promise for treating stroke, aneurysm, subarachnoid hemorrhage and other neurological or neurotraumatic conditions. The chloride salt of TAT-NR2B9c shows improved stability compared with the acetate salt form of prior formulations. Formulations of the chloride salt of TAT-NR2B9c are stable at ambient temperature thus facilitating maintenance of supplies of such a formulation in ambulances for administration at the scene of illness or accident or in transit to a hospital.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.