Patent · US Active

Polypeptides binding to human complement C5

US10206975B2 · kind B2 · utility

2Cited by

6References

22Claims

0Family size

Assignee

SWEDISH ORPHAN BIOVITRUM AG · SE

Inventors

Charlotta Berghard · Stockholm, SE
Magnus Berglund · Handen, SE
Patrik Strömberg · Sollentuna, SE
Malin Lindborg · Boo, SE
Elin Gunneriusson · Hallsberg, SE
Joachim Feldwisch · Tyresö, SE

Key dates

Filing date	Sep 29, 2017
Grant date	Feb 19, 2019
Priority date	—
Expiry date	Sep 29, 2037

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/31
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to C5 binding polypeptides, comprising a C5 binding motif, BM, which motif consists of an amino acid sequence selected from i) EX2X3X4A X6 X7EID X11LPNL X16X17X18QW X21AFIX25X26LX28D, and ii) an amino acid sequence which has at least 86% identity to the sequence defined in i), wherein the polypeptide binds to C5. The present invention moreover relates to C5 binding polypeptides for use in therapy, such as for use in treatment of a C5 related condition, and to methods of treatment.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.