Salts and prodrugs of 1-methyl-D-tryptophan
US10207990B2 · kind B2 · utility
1Cited by
12References
27Claims
0Family size
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Key dates
| Filing date | Jun 27, 2017 |
| Grant date | Feb 19, 2019 |
| Priority date | — |
| Expiry date | Jul 20, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/65742
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Presently provided are indoximod prodrug and salt compounds and pharmaceutical compositions comprising salts and prodrugs of indoximod, that produce enhanced plasma concentration and exposure to indoximod compared to direct administration of indoximod, in patients in need of treatment of immunosuppression mediated by the indoleamine-2,3-dioxygenase pathway, such as patients with cancer or chronic infectious diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.