Process for the preparation of Apixaban and intermediates thereof
US10208036B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Sep 6, 2017 |
| Grant date | Feb 19, 2019 |
| Priority date | — |
| Expiry date | Sep 6, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/86
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention refers to novel process for the preparation of Apixaban. Further, the invention also related to a process for the preparation of intermediate of Apixaban from very basic and cheap row material i.e. Aniline which is widely commercially available. The present invention provides process for preparation of Apixaban using a different sequence of synthetic steps and does not involve use of Ullmann reaction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.