Imidazopyridazine compounds and their use

US10208066B2 · kind B2 · utility

Assignee

• HUTCHISON MEDIPHARMA LIMITED · CN

Inventors

• Wei-Guo Su · Shanghai, CN
• Guangxiu Dai · Shanghai, CN
• Welhan Zhang · Shanghai, CN
• Wei Deng · Shanghai, CN

Key dates

• Filing date: Sep 23, 2015
• Grant date: Feb 19, 2019
• Expiry date: Sep 23, 2035

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D487/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This disclosure provides novel imidazopyridazine compounds of formula (I) and pharmaceutical acceptable salt thereof, pharmaceutical compositions containing them, a process for preparing them, and their practical effect in inhibiting PI3K and potential use in treating a disease responsive to inhibition of PI3K, for example, an inflammatory disease, autoimmune disease or cancer.