Angiopoietin-2 specific TIE2 receptor
US10208100B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Dec 20, 2013 |
| Grant date | Feb 19, 2019 |
| Priority date | — |
| Expiry date | May 10, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y207/10001
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In one aspect, provided herein is a polypeptide comprising a modified angiopoietin receptor or fragment thereof, wherein the polypeptide binds preferentially to angiopoietin-2 compared to angiopoietin-1. Nucleic acid sequences encoding the polypeptide, as well as pharmaceutical uses of the polypeptide in treating diseases such as cancer and inflammation are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.