Artificially produced polyclonal immunoglobulin preparation
US10208131B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Dec 17, 2012 |
| Grant date | Feb 19, 2019 |
| Priority date | — |
| Expiry date | Apr 20, 2033 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/53
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention intended to provide an artificial polyclonal immunoglobulin composition having a high therapeutic effect and high safety, and being capable of stable supply in a large amount. Specifically provided is an artificial polyclonal immunoglobulin composition containing, as active ingredients, 204 polypeptides represented by amino acid sequences set forth in SEQ ID NOS: 1 to 204 of the sequence listing, the polypeptides being plural kinds of single chain variable fragments (also referred to as ScFvs) each comprised of a heavy chain variable region, heavy chain constant region 1, and hinge region (VH-CH1-hinge) of an immunoglobulin, in which the heavy chain variable regions are different each other.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.