Method for generating high-titer hepatitis E virus stocks and titration assay for hepatitis E virus
US10208291B2 · kind B2 · utility
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Key dates
| Filing date | Jul 19, 2016 |
| Grant date | Feb 19, 2019 |
| Priority date | — |
| Expiry date | Oct 12, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/28151
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Polybrene as an additive in cell culture medium is used in methods for the generation of high-titer hepatitis E virus stocks and assays for titration of hepatitis E virus. A cell culture medium containing polybrene is used for high-titer HEV generation, a method for determining the presence and/or the level of HEV in a sample, and an HEV titration assay using polybrene.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.