Compounds and methods for inhibiting production of trimethylamine
US10213407B2 · kind B2 · utility
0Cited by
3References
19Claims
0Family size
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Inventors
Key dates
| Filing date | Dec 1, 2016 |
| Grant date | Feb 26, 2019 |
| Priority date | — |
| Expiry date | Dec 1, 2036 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a method of inhibiting the conversion of choline or carnitine to trimethylamine (TMA) and lowering TMAO in an individual comprising administering to the individual a composition comprising a compound set forth in FORMULA (I): The invention also provides for a method of inhibiting the production of TMA by bacteria comprising administering to the individual a composition comprising a compound set forth in FORMULA (I) wherein the compound is administered in an amount effective to inhibit formation of trimethylamine (TMA) from choline or carnitine in the individual.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.