Substituted benzoxazolone derivatives as acid ceramidase inhibitors, and their use as medicaments
US10213416B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Nov 8, 2016 |
| Grant date | Feb 26, 2019 |
| Priority date | — |
| Expiry date | Nov 8, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D263/58
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to substituted benzoxazolone derivatives as acid ceramidase inhibitors, pharmaceutical compositions containing these inhibitors and methods of inhibiting acid ceramidase for the treatment of disorders in which modulation of the levels of ceramide is clinically relevant. The invention also provides substituted benzoxazolone derivatives for use in the treatment of cancer, inflammation, pain, inflammatory pain or pulmonary diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.