Fatty acids as anti-inflammatory agents

US10213417B2 · kind B2 · utility

Assignee

• University of Pittsburgh—Of the Commonwealth System of Higher Education · US

Inventors

• Bruce A. Freeman · Pittsburgh, US
• Francisco J. Schopfer · Pittsburgh, US

Key dates

• Filing date: Jul 27, 2017
• Grant date: Feb 26, 2019
• Expiry date: Aug 2, 2037

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of formula I and their metabolites are potent mediators of an inflammatory response: where a, b, c, d, e, f, V, W, X, Y, Ra, Ra′, Rb, Rb′, Rc, and Rc′ are defined herein. In particular, the compounds of the invention are candidate therapeutics for treating inflammatory conditions.