System and method for optogenetic therapy
US10213617B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 28, 2014 |
| Grant date | Feb 26, 2019 |
| Priority date | — |
| Expiry date | Apr 18, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2005/0665
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Configurations are described for utilizing light-activated proteins within cell membranes and subcellular regions to assist with medical treatment paradigms, such as hypertension treatment via anatomically specific and temporally precise modulation of renal plexus activity. The invention provides for proteins, nucleic acids, vectors and methods for genetically targeted expression of light-sensitive proteins to specific cells or defined cell populations. In particular the invention provides systems, devices, and methods for millisecond-timescale temporal control of certain cell activities using moderate light intensities, such as the generation or inhibition of electrical spikes in nerve cells and other excitable cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.