Patent · US Active

Hot melt fragmentation extruder and process

US10213948B2 · kind B2 · utility

0Cited by
4References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 13, 2018
Grant dateFeb 26, 2019
Priority date
Expiry dateMar 13, 2038

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB29K2105/0035
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A co-rotating twin screw extruder for forming fragments is disclosed. The extruder comprises of an intake zone for receiving one or more excipient(s) suitable for oral dosage or one or more excipient(s) suitable for oral dosage along with one or more active pharmaceutical ingredient, a melt zone for softening at least one excipient to form a viscous mass or melt and a fragmenting zone for fragmenting and cooling the viscous mass into cooled fragments and an extruder outlet for recovering the cooled fragments from the extruder.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.