Modified macrocyclic compounds

US10214542B2 · kind B2 · utility

Assignee

• Bayer Pharma Aktiengesellschaft · DE

Inventors

• Ulrich Lücking · Berlin, DE
• Daniel Hog · Düsseldorf, DE
• Jens Geisler · Berlin, DE
• Arne Scholz · Berlin, DE
• Kirstin Petersen · Berlin, DE
• Philip Lienau · Berlin, DE
• Christian Stegmann · Berlin, DE
• Dorothee Andres · Potsdam, DE
• Gerhard Siemeister · Berlin, DE
• Nicolas Werbeck · Berlin, DE

Key dates

• Filing date: Sep 30, 2016
• Grant date: Feb 26, 2019
• Expiry date: Sep 30, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D515/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel modified macrocyclic compounds of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).