Cell differentiation devices and methods
US10214762B2 · kind B2 · utility
0Cited by
0References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 28, 2015 |
| Grant date | Feb 26, 2019 |
| Priority date | — |
| Expiry date | Oct 28, 2035 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2300/069
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Methods, devices, and kits are provided for identifying, selecting, and/or manipulating live cells in a sample comprising a suspected mixed population of cells by subjecting the sample located in a first position to a linear gradient of a cellular stimulus to induce a change in a live cell sufficient to induce movement of the cell from a first position to a second position, wherein a dead cell, if present in the sample, is not induced to move to the second position in the presence of the cellular stimulus; and identifying or selecting the live cell in the second position.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.