Vaccines against Streptococcus pneumoniae serotype 8

US10220083B2 · kind B2 · utility

Assignee

• Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V. · US

Inventors

• Peter H. Seeberger · Potsdam, DE
• Claney Lebev Pereira · Berlin, DE
• Chakkumkal Anish · The Hague, NL
• Benjamin Schumann · Berlin, DE
• Sharavathi Guddehalli Parameswarappa · Berlin, DE
• Heung Sik Hahm · Charlottesville, US
• Subramanian Govindan · Viralimalai, IN

Key dates

• Filing date: Sep 28, 2015
• Grant date: Mar 5, 2019
• Expiry date: Sep 28, 2035

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/3156
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to synthetic saccharides of general formula (I) that are related to Streptococcus pneumoniae serotype 8 capsular polysaccharide, conjugates thereof and the use of said saccharides and conjugates for raising a protective immune response in a human and/or animal host. Furthermore, the synthetic saccharide structures of general formula (I) are useful as marker in immunological assays for detection of antibodies against Streptococcus pneumoniae bacteria.