Patent · US Active

Inhibitors of plasma kallikrein

US10221161B2 · kind B2 · utility

13Cited by
1References
32Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 14, 2014
Grant dateMar 5, 2019
Priority date
Expiry dateAug 14, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides compounds of formula (I), compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, R12, R13, A, L, B, n, W, X, Y and Z are as defined herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.