Flavone based EGFR inhibitors and process for preparation thereof
US10221165B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Feb 3, 2016 |
| Grant date | Mar 5, 2019 |
| Priority date | — |
| Expiry date | Feb 3, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention discloses a novel EGFR inhibitor compound of formula (1), process for preparation thereof and methods of treating abnormal cell growth in mammals by administering the compounds of formula (1) wherein, R is selected from hydrogen, alkyl, nitro, halogens such as chlorine, bromine, fluorine and iodine; R1=hydrogen, alkyl, alkoxy, aryl, nitro, halogens such as chlorine, bromine, fluorine and iodine, trifluoromethyl, thioalkyl, trifluromethoxy, trialkylsilyl.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.