Method and device for detecting and assessing reactive hyperemia using segmental plethysmography
US10226186B2 · kind B2 · utility
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6References
18Claims
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Key dates
| Filing date | Sep 8, 2017 |
| Grant date | Mar 12, 2019 |
| Priority date | — |
| Expiry date | Sep 8, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16Z99/00
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method for measuring reactive hyperemia in a subject is disclosed. The method includes performing a first segmental cuff plethysmography to generate a baseline arterial compliance curve and/or a baseline pressure-area (P-A) curve, performing a second segmental cuff plethysmography to generate a hyperemic arterial compliance curve and/or a hyperemic P-A curve, and calculating an area between the baseline and the hyperemic curves. The size of the area can be used as an indication of endothelial dysfunction (ED) and ED-related diseases.
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