Benzoxazolone derivatives as acid ceramidase inhibitors, and their use as medicaments
US10226452B2 · kind B2 · utility
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1References
21Claims
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Key dates
| Filing date | Nov 8, 2016 |
| Grant date | Mar 12, 2019 |
| Priority date | — |
| Expiry date | Nov 8, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to benzoxazolone derivatives as acid ceramidase inhibitors, pharmaceutical compositions containing these inhibitors and methods of inhibiting acid ceramidase for the treatment of disorders in which modulation of the levels of ceramide is clinically relevant. The invention also provides benzoxazolone derivatives for use as a medicament in the treatment of cancer, inflammation, pain, inflammatory pain or pulmonary diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.