Method for selection of high M6P recombinant proteins
US10227577B2 · kind B2 · utility
7Cited by
48References
10Claims
0Family size
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Key dates
| Filing date | Mar 30, 2017 |
| Grant date | Mar 12, 2019 |
| Priority date | — |
| Expiry date | Mar 30, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods for the production, capturing and purification of recombinant human lysosomal proteins are described. Such recombinant human lysosomal proteins can have high content of mannose-6-phosphate residues. Also described are pharmaceutical compositions comprising such recombinant human lysosomal proteins, as well as methods of treatment and uses of such recombinant human lysosomal proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.