Methods, systems, and compositions for cell-derived/vesicle-based microRNA delivery
US10227593B2 · kind B2 · utility
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14Claims
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Key dates
| Filing date | Dec 23, 2016 |
| Grant date | Mar 12, 2019 |
| Priority date | — |
| Expiry date | Dec 23, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Some embodiments comprise methods, systems, and compositions to produce and/or administer modified exosomes or other vesicles containing one or more selected microRNAs, including but not limited to, miR-146b. Some embodiments also comprise the therapeutic administration and use of such modified exosomes and/or producer cells to treat mammalian brain or neurologic injuries and diseases, including in human beings.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.