Patent · US Active

Modified parvovirus useful for gene silencing

US10227609B2 · kind B2 · utility

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5Claims

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Assignee

Deutsches Krebsforschungszentrum · DE

Inventors

Antonio Marchini · Heidelberg, DE
Jean Rommelaere · Heidelberg, DE
Barbara Leuchs · Heidelberg, DE
Anna Illarionova · Heidelberg, DE

Key dates

Filing date	Jan 25, 2013
Grant date	Mar 12, 2019
Priority date	—
Expiry date	Jan 25, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2750/14343
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Described are methods for efficiently down regulating the expression of a gene of interest in a cell by use of a modified rodent parvovirus that contains an expressible target specific nucleic acid, preferably an shRNA expression cassette. Also described are cells or organisms comprising said parvovirus.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.