SIK inhibitor for use in a method of treating an inflammatory and/or immune disorder
US10233157B2 · kind B2 · utility
9Cited by
5References
26Claims
0Family size
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Key dates
| Filing date | May 26, 2017 |
| Grant date | Mar 19, 2019 |
| Priority date | — |
| Expiry date | May 26, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the discovery that salt inducible kinases (SIKs) suppress the formation of anti-inflammatory molecules such as IL-10, which are important for the resolution of inflammation and identifies SIK inhibitors that may be used to treat disorders associated with undesirable inflammation, such as inflammatory bowel disease and/or autoimmune disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.