Tenofovir monobenzyl ester phosphamide prodrug, preparation method and use thereof
US10233202B2 · kind B2 · utility
0Cited by
0References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 26, 2016 |
| Grant date | Mar 19, 2019 |
| Priority date | — |
| Expiry date | May 26, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/6561
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a tenofovir monobenzyl ester phosphamide prodrug, preparation method and pharmaceutical use thereof. Specifically, the present invention relates to a compound of general formula (X), or isomer, pharmaceutically-acceptable salt, hydrate or solvate thereof, preparation method and use thereof in the preparation of drugs for treating viral infectious diseases, preferably AIDS infection, hepatitis B or diseases caused by hepatitis B virus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.