Isoform of the TGF-beta receptor II
US10233227B2 · kind B2 · utility
0Cited by
1References
6Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Dec 19, 2014 |
| Grant date | Mar 19, 2019 |
| Priority date | — |
| Expiry date | Dec 19, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16043
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An isoform of the TGF beta receptor II comprising a sequence of about of 80 amino acids and lacking a transmembrane domain; wherein the isoform is a TGFβ-1 agonist. The isoform comprises the amino acid sequence set forth in SEQ ID No. 12. The isoform may have the amino acid sequence set forth in SEQ ID No. 2 or sequences having at least 85% sequence identity to the sequence set forth in SEQ ID No. 2.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.