Microfluidics cell culture device

US10233415B1 · kind B1 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Anurag Mathur · Berkeley, US
• Peter Loskill · Stuttgart, DE
• Luke P. Lee · Orinda, US
• Kevin E. Healy · Moraga, US
• Soongweon Hong · Berkeley, US

Key dates

• Filing date: Jul 21, 2014
• Grant date: Mar 19, 2019
• Expiry date: Nov 28, 2035

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01L2400/086
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present disclosure provides a microfluidics device for culturing cells, such as cardiomyocytes or cardiomyocyte progenitors; and methods of culturing cells using the device. The device and culturing methods find use in drug screening methods, for methods of evaluating a drug under development, and for methods of predicting patient response to a given treatment regimen, which methods are also provided.