Methods and systems for rapid detection of microorganisms using free antibodies

US10233484B2 · kind B2 · utility

Assignee

• LABORATORY CORPORATION OF AMERICA HOLDINGS · US

Inventors

• Dwight Lyman Anderson · Minneapolis, US
• Ben Barrett Hopkins · West Hollywood, US
• Jose S. Gil · Calabasas, US
• Stephen Erickson · Birchwood Village, US
• Ekaterina Kovacheva · Gardena, US

Key dates

• Filing date: Feb 18, 2015
• Grant date: Mar 19, 2019
• Expiry date: Feb 18, 2035

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2469/10
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Disclosed herein are methods and systems for detection of a microorganism of interest using an amplification assay. The methods and systems utilize the specificity of binding agents, such as antibodies, to rapidly detect low levels of a specific microorganism present in a sample. In certain embodiments, antibodies are bound to a large number of the available binding sites on a microorganism.